TRAIL induces autophagic protein cleavage through caspase activation in melanoma cell lines under arginine deprivation

Arginine deprivation is a promising strategy for treating ASS-negative malignant tumors including melanoma. However, autophagy can potentially counteract the effectiveness of this treatment by acting as a pro-survival pathway. By combining TRAIL (tumor necrosis factor-related apoptosis-inducing liga...

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Bibliographic Details
Main Authors: You, Min, Savaraj, Niramol, Kuo, Macus T., Wangpaichitr, Medhi, Varona-Santos, Javier, Wu, Chunjing, Nguyen, Dao M., Feun, Lynn
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771696/
https://ncbi.nlm.nih.gov/pubmed/23180246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-012-1518-1
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