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The combination of ADI-PEG20 and TRAIL effectively increases cell death in melanoma cell lines
Current treatment for advanced, metastatic melanoma is not very effective, and new modalities are needed. ADI-PEG20 is a drug that specifically targets ASS-negative malignant melanomas while sparing the ASS-expressing normal cells. Although laboratory research and clinical trials showed promising re...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860865/ https://ncbi.nlm.nih.gov/pubmed/20227389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.03.066 |
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