Gas6/Axl in arginine-starvation therapy

Por Tsai, Wen-Bin, Long, Yan, Kuo, Macus Tien
Publicado no Oncoscience (2015)

Functional interaction between FOXO3a and ATM regulates DNA damage response

Por Tsai, Wen-Bin, Chung, Young Min, Takahashi, Yoko, Xu, Zhaohui, Hu, Mickey C-T.
Publicado em 2008

Specificity Protein 1 (Sp1) Oscillation Is Involved in Copper Homeostasis Maintenance by Regulating Human High-Affinity Copper Transporter 1 Expression

Por Liang, Zheng D., Tsai, Wen-Bin, Lee, Mei-Yi, Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2012

Resistance to Arginine Deiminase Treatment in Melanoma Cells Is Associated with Induced Argininosuccinate Synthetase Expression involving c-Myc/HIF-1α/Sp4

Por Tsai, Wen-Bin, Aiba, Isamu, Lee, Soo-yong, Feun, Lynn, Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2009

Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

Por Tsai, Wen-Bin, Aiba, Isamu, Long, Yan, Lin, Hui-Kuan, Feun, Lynn, Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2012

Arginine Deiminase Resistance in Melanoma Cells Is Associated with Metabolic Reprogramming, Glucose Dependence and Glutamine Addiction

Por Long, Yan, Tsai, Wen-Bin, Wangpaichitr, Medhi, Tsukamoto, Takashi, Savaraj, Niramol, Feun, Lynn G., Kuo, Macus Tien
Publicado em 2013

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors

Por Kuo, Macus Tien, Long, Yan, Tsai, Wen-Bin, Li, Ying-Ying, Chen, Helen H.W., Feun, Lynn G., Savaraj, Niramol
Publicado no Transl Oncol (2019)

Inhibition of FOXO3 Tumor Suppressor Function by βTrCP1 through Ubiquitin-Mediated Degradation in a Tumor Mouse Model

Por Tsai, Wen-Bin, Chung, Young Min, Zou, Yiyu, Park, See-Hyoung, Xu, Zhaohui, Nakayama, Keiko, Lin, Sue-Hwa, Hu, Mickey C-T.
Publicado em 2010

Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression

Por Tsai, Wen-Bin, Long, Yan, Chang, Jeffrey T., Savaraj, Niramol, Feun, Lynn G., Jung, Manfred, Chen, Helen H. W., Kuo, Macus Tien
Publicado no Sci Rep (2017)

Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis

Por Zou, Yiyu, Tsai, Wen-Bin, Cheng, Chien-Jui, Hsu, Chiun, Chung, Young Min, Li, Pao-Chen, Lin, Sue-Hwa, Hu, Mickey CT
Publicado em 2008

FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damage

Por Chung, Young Min, Park, See-Hyoung, Tsai, Wen-Bin, Wang, Shih-Ya, Ikeda, Masa-Aki, Berek, Jonathan S., Chen, David J., Hu, Mickey C-T.
Publicado em 2012

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is ind...

Por Long, Yan, Tsai, Wen-Bin, Chang, Jeffrey T., Estecio, Marcos, Wangpaichitr, Medhi, Savaraj, Naramol, Feun, Lynn G., Chen, Helen H.W., Kuo, Macus Tien
Publicado no Oncotarget (2016)

Gas6/Axl is the sensor of Arginine-Auxotrophic Response in Targeted Chemotherapy with Arginine-Depleting Agents

Por Tsai, Wen-Bin, Long, Yan, Park, Jeong-Ran, Chang, Jeffrey T., Liu, Hui, Rodriguez-Canales, Jaime, Savaraj, Niramol, Feun, Lynn G., Davies, Michael A., Wistuba, Ignacio I, Kuo, Macus Tien
Publicado no Oncogene (2015)

Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy

Por Chen, Helen HW, Chen, Wen-Chung, Liang, Zhang-Dong, Tsai, Wen-Bin, Long, Yan, Aiba, Isamu, Fu, Siqing, Broaddus, Russell, Liu, Jinsong, Feun, Lynn G, Savaraj, Niramol, Kuo, Macus Tien
Publicado no Expert Opin Ther Targets (2015)

Mechanistic Basis for Overcoming Platinum Resistance Using Copper Chelating Agents

Por Liang, Zheng D., Long, Yan, Tsai, Wen-Bin, Fu, Siqing, Kurzrock, Razelle, Gagea-Iurascu, Mihai, Zhang, Fan, Chen, Helen H.W., Hennessy, Bryan T., Mills, Gordon B., Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2012