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Mechanistic Basis for Overcoming Platinum Resistance Using Copper Chelating Agents

Platinum (Pt)-based antitumor agents are widely used in cancer chemotherapy. Drug resistance is a major obstacle to the successful use of these agents because once drug resistance develops, other effective treatment options are limited. Recently, we have conducted a clinical trial using a copper (Cu...

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Detalhes bibliográficos
Main Authors: Liang, Zheng D., Long, Yan, Tsai, Wen-Bin, Fu, Siqing, Kurzrock, Razelle, Gagea-Iurascu, Mihai, Zhang, Fan, Chen, Helen H.W., Hennessy, Bryan T., Mills, Gordon B., Savaraj, Niramol, Kuo, Macus Tien
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496003/
https://ncbi.nlm.nih.gov/pubmed/22914438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0580
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