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Overcoming Platinum Drug Resistance with Copper-lowering Agents

Platinum (Pt)-based antitumor agents have been the mainstay of cancer chemotherapy for the last three decades. While multiple mechanisms are responsible for treatment failure, deficiency in drug transport is an important contributor. The human high-affinity copper (Cu) transporter-1 (hCtr1) can also...

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Detalhes bibliográficos
Main Authors: CHEN, HELEN H.W., KUO, MACUS TIEN
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001922/
https://ncbi.nlm.nih.gov/pubmed/24122978
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