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Overcoming Platinum Drug Resistance with Copper-lowering Agents

Platinum (Pt)-based antitumor agents have been the mainstay of cancer chemotherapy for the last three decades. While multiple mechanisms are responsible for treatment failure, deficiency in drug transport is an important contributor. The human high-affinity copper (Cu) transporter-1 (hCtr1) can also...

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Détails bibliographiques
Auteurs principaux: CHEN, HELEN H.W., KUO, MACUS TIEN
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001922/
https://ncbi.nlm.nih.gov/pubmed/24122978
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