Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy

od Chen, Helen H. W., Kuo, Macus Tien
Wydane 2010

Overcoming Platinum Drug Resistance with Copper-lowering Agents

od CHEN, HELEN H.W., KUO, MACUS TIEN
Wydane 2013

Improving radiotherapy in cancer treatment: Promises and challenges

od Chen, Helen H.W., Kuo, Macus Tien
Wydane w Oncotarget (2017)

Role of the Human High-Affinity Copper Transporter (hCtr1) in Copper Homeostasis Regulation and Cisplatin Sensitivity in Cancer Chemotherapy

od Kuo, Macus Tien, Fu, Siqing, Savaraj, Niramol, Chen, Helen H. W.
Wydane 2012

Effects of Cu(II) and cisplatin on the stability of Specific protein 1 (Sp1)-DNA binding: Insights into the regulation of copper homeostasis and platinum drug transport

od Yan, Dong, Aiba, Isamu, Chen, Helen H W, Kuo, Macus Tien
Wydane w J Inorg Biochem (2016)

Modulating Chemosensitivity of Tumors to Platinum-Based Antitumor Drugs by Transcriptional Regulation of Copper Homeostasis

od Lai, Yu-Hsuan, Kuo, Chin, Kuo, Macus Tien, Chen, Helen H. W.
Wydane w Int J Mol Sci (2018)

Targeting the Proline–Glutamine–Asparagine–Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

od Kuo, Macus Tien, Chen, Helen H. W., Feun, Lynn G., Savaraj, Niramol
Wydane w Pharmaceuticals (Basel) (2021)

Targeting the Copper Transport System to Improve Treatment Efficacies of Platinum-Containing Drugs in Cancer Chemotherapy

od Kuo, Macus Tien, Huang, Yu-Fang, Chou, Cheng-Yang, Chen, Helen H. W.
Wydane w Pharmaceuticals (Basel) (2021)

Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals

od Liang, Zheng Dong, Long, Yan, Chen, Helen H. W., Savaraj, Niramol, Kuo, Macus Tien
Wydane 2013

Association of Primary Treatment Modality for Advanced-Stage Oropharyngeal Squamous Cell Carcinoma With Survival Outcomes

od Tsai, Mu-Hung, Cheng, Yung-Jen, Pao, Tzu-Hui, Hsueh, Wei-Ting, Chen, Helen H.W., Wu, Yuan-Hua
Wydane w JAMA Netw Open (2021)

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors

od Kuo, Macus Tien, Long, Yan, Tsai, Wen-Bin, Li, Ying-Ying, Chen, Helen H.W., Feun, Lynn G., Savaraj, Niramol
Wydane w Transl Oncol (2019)

Transcription Factor Sp1 Plays an Important Role in the Regulation of Copper Homeostasis in Mammalian Cells

od Song, Im-Sook, Chen, Helen H. W., Aiba, Isamu, Hossain, Anwar, Liang, Zheng D., Klomp, Leo W. J., Kuo, Macus Tien
Wydane 2008

Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression

od Tsai, Wen-Bin, Long, Yan, Chang, Jeffrey T., Savaraj, Niramol, Feun, Lynn G., Jung, Manfred, Chen, Helen H. W., Kuo, Macus Tien
Wydane w Sci Rep (2017)

Wheat germ agglutinin-induced paraptosis-like cell death and protective autophagy is mediated by autophagy-linked FYVE inhibition

od Tsai, Tsung Lin, Wang, Hao Chen, Hung, Chun Hua, Lin, Peng Chan, Lee, Yi San, Chen, Helen H.W., Su, Wu Chou
Wydane w Oncotarget (2017)

Molecular diagnosis of primary liver cancer by microsatellite DNA analysis in the serum

od Chang, Y-C, Ho, C-L, Chen, Helen H-W, Chang, T-T, Lai, W-W, Dai, Y-C, Lee, W-Y, Chow, N-H
Wydane 2002

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is ind...

od Long, Yan, Tsai, Wen-Bin, Chang, Jeffrey T., Estecio, Marcos, Wangpaichitr, Medhi, Savaraj, Naramol, Feun, Lynn G., Chen, Helen H.W., Kuo, Macus Tien
Wydane w Oncotarget (2016)

Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy

od Chen, Helen H.W., Yan, Jiang-Jou, Chen, Wen-Chung, Kuo, Macus Tien, Lai, Yu-Hsuan, Lai, Wu-Wei, Liu, Hsiao-Sheng, Su, Wu-Chou
Wydane 2011

Activation of the Signal Transducer and Activator of Transcription 3 Pathway Up-Regulates Estrogen Receptor-β Expression in Lung Adenocarcinoma Cells

od Wang, Hao-Chen, Yeh, Hsuan-Heng, Huang, Wei-Lun, Lin, Chien-Chung, Su, Wen-Pin, Chen, Helen H. W., Lai, Wu-Wei, Su, Wu-Chou
Wydane w Mol Endocrinol (2011)

Mechanistic Basis for Overcoming Platinum Resistance Using Copper Chelating Agents

od Liang, Zheng D., Long, Yan, Tsai, Wen-Bin, Fu, Siqing, Kurzrock, Razelle, Gagea-Iurascu, Mihai, Zhang, Fan, Chen, Helen H.W., Hennessy, Bryan T., Mills, Gordon B., Savaraj, Niramol, Kuo, Macus Tien
Wydane 2012

ELEVATED GLUTATHIONE LEVELS CONFER CELLULAR SENSITIZATION TO CISPLATIN TOXICITY BY UPREGULATION OF COPPER TRANSPORTER HCTR1

od Chen, Helen H. W., Song, Im-Sook, Hossain, Anwar, Choi, Min-Koo, Yamane, Yoshiaki, Liang, Zheng D., Lu, Jia, Wu, Lily Y-H, Siddik, Zahid H., Klomp, Leo W. J., Savaraj, Niramol, Tien, Kuo Macus
Wydane 2008