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Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals

Platinum-based antitumor agents have been the mainstay in cancer chemotherapy for many human malignancies. Drug resistance is an important obstacle to achieving the maximal therapeutic efficacy of these drugs. Understanding how platinum drugs enter cells is of great importance in improving therapeut...

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Hlavní autoři: Liang, Zheng Dong, Long, Yan, Chen, Helen H. W., Savaraj, Niramol, Kuo, Macus Tien
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889686/
https://ncbi.nlm.nih.gov/pubmed/24132751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-013-1051-z
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