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Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals

Platinum-based antitumor agents have been the mainstay in cancer chemotherapy for many human malignancies. Drug resistance is an important obstacle to achieving the maximal therapeutic efficacy of these drugs. Understanding how platinum drugs enter cells is of great importance in improving therapeut...

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Autors principals: Liang, Zheng Dong, Long, Yan, Chen, Helen H. W., Savaraj, Niramol, Kuo, Macus Tien
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889686/
https://ncbi.nlm.nih.gov/pubmed/24132751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-013-1051-z
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