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Targeting the Proline–Glutamine–Asparagine–Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

Proline, glutamine, asparagine, and arginine are conditionally non-essential amino acids that can be produced in our body. However, they are essential for the growth of highly proliferative cells such as cancers. Many cancers express reduced levels of these amino acids and thus require import from t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmaceuticals (Basel)
Main Authors: Kuo, Macus Tien, Chen, Helen H. W., Feun, Lynn G., Savaraj, Niramol
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830038/
https://ncbi.nlm.nih.gov/pubmed/33477430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010072
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