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Targeting the Proline–Glutamine–Asparagine–Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

Proline, glutamine, asparagine, and arginine are conditionally non-essential amino acids that can be produced in our body. However, they are essential for the growth of highly proliferative cells such as cancers. Many cancers express reduced levels of these amino acids and thus require import from t...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Kuo, Macus Tien, Chen, Helen H. W., Feun, Lynn G., Savaraj, Niramol
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830038/
https://ncbi.nlm.nih.gov/pubmed/33477430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010072
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