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Pegylated arginine deiminase: a novel anticancer enzyme agent

Pegylated arginine deiminase (ADI-PEG20) is a novel anticancer enzyme that produces depletion of arginine, which is a nonessential amino acid in humans. Certain tumours, such as malignant melanoma and hepatocellular carcinoma, are auxotrophic for arginine. These tumours that are sensitive to arginin...

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Bibliografiska uppgifter
Huvudupphovsmän: Feun, Lynn, Savaraj, Niramol
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086545/
https://ncbi.nlm.nih.gov/pubmed/16787144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.15.7.815
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