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Pegylated arginine deiminase: a novel anticancer enzyme agent
Pegylated arginine deiminase (ADI-PEG20) is a novel anticancer enzyme that produces depletion of arginine, which is a nonessential amino acid in humans. Certain tumours, such as malignant melanoma and hepatocellular carcinoma, are auxotrophic for arginine. These tumours that are sensitive to arginin...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086545/ https://ncbi.nlm.nih.gov/pubmed/16787144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.15.7.815 |
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