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Transcription Factor Sp1 Plays an Important Role in the Regulation of Copper Homeostasis in Mammalian Cells
Copper is an essential metal nutrient, yet Cu overload is toxic. Here, we report that human copper transporter 1 (hCtr1) plays an important role in the maintenance of Cu homeostasis by demonstrating that expression of hCtr1 mRNA was up-regulated under Cu-depleted conditions and down-regulated under...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574735/ https://ncbi.nlm.nih.gov/pubmed/18483225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.046771 |
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