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Elevated GSH level increases cadmium resistance through downregulation of Sp1-dependent expression of the cadmium transporter ZIP8
Cadmium is a non-essential toxic metal in mammals. Its toxicity is mainly caused by interactions with cellular proteins that result in protein dysfunction and the disturb normal cellular functions. Glutathione (GSH) has been reported to play a role in cadmium resistance by serving as a cofactor for...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574563/ https://ncbi.nlm.nih.gov/pubmed/18556457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.046862 |
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