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Elevated GSH level increases cadmium resistance through downregulation of Sp1-dependent expression of the cadmium transporter ZIP8

Cadmium is a non-essential toxic metal in mammals. Its toxicity is mainly caused by interactions with cellular proteins that result in protein dysfunction and the disturb normal cellular functions. Glutathione (GSH) has been reported to play a role in cadmium resistance by serving as a cofactor for...

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Main Authors: Aiba, Isamu, Hossain, Anwar, Tien Kuo, Macus
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574563/
https://ncbi.nlm.nih.gov/pubmed/18556457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.046862
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