From delocalized lipophilic cations to hypoxia: Blocking tumor cell mitochondrial function leads to therapeutic gain with glycolytic inhibitors

Por Kurtoglu, Metin, Lampidis, Theodore J.
Publicado em 2009

Intrinsically lower AKT, mTOR and HIF activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines

Por Wangpaichitr, Medhi, Savaraj, Niramol, Maher, Johnathan, Kurtoglu, Metin, Lampidis, Theodore J.
Publicado em 2008

High endoplasmic reticulum activity renders multiple myeloma cells hypersensitive to mitochondrial inhibitors

Por Kurtoglu, Metin, Philips, Katherine, Liu, Huaping, Boise, Lawrence H., Lampidis, Theodore J.
Publicado em 2009

Activation of the Unfolded Protein Response by 2-Deoxy-d-Glucose Inhibits Kaposi's Sarcoma-Associated Herpesvirus Replication and Gene Expression

Por Leung, Howard J., Duran, Elda M., Kurtoglu, Metin, Andreansky, Samita, Lampidis, Theodore J., Mesri, Enrique A.
Publicado em 2012

2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

Por Xi, Haibin, Kurtoglu, Metin, Liu, Huaping, Wangpaichitr, Medhi, You, Min, Liu, Xiongfei, Savaraj, Niramol, Lampidis, Theodore J.
Publicado em 2010

Focal, Periocular Delivery of 2-Deoxy-d-Glucose as Adjuvant to Chemotherapy for Treatment of Advanced Retinoblastoma

Por Piña, Yolanda, Houston, Samuel K., Murray, Timothy G., Boutrid, Hinda, Celdran, Magda, Feuer, William, Shi, Wei, Hernandez, Eleut, Lampidis, Theodore J.
Publicado em 2010

Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-d-glucose

Por Philips, Katherine B., Kurtoglu, Metin, Leung, Howard J., Liu, Huaping, Gao, Ningguo, Lehrman, Mark A., Murray, Timothy G., Lampidis, Theodore J.
Publicado no Cancer Chemother Pharmacol (2013)

2-DEOXY-GLUCOSE DOWN REGULATES ENDOTHELIAL AKT AND ERK VIA INTERFERENCE WITH N-LINKED GLYCOSYLATION, INDUCTION OF ENDOPLASMIC RETICULUM STRESS AND GSK-3β ACTIVATION

Por Kovács, Krisztina, Decatur, Christina, Toro, Marcela, Pham, Dien G., Liu, Huaping, Jing, Yuqi, Murray, Timothy G., Lampidis, Theodore J., Merchan, Jaime R.
Publicado no Mol Cancer Ther (2015)

Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress

Por Leclerc, Guy J., DeSalvo, Joanna, Du, Jianfeng, Gao, Ningguo, Leclerc, Gilles M., Lehrman, Mark A., Lampidis, Theodore J., Barredo, Julio C
Publicado no Leuk Res (2015)

Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

Por Liu, Huaping, Kurtoglu, Metin, León-Annicchiarico, Clara Lucia, Munoz-Pinedo, Cristina, Barredo, Julio, Leclerc, Guy, Merchan, Jaime, Liu, Xiongfei, Lampidis, Theodore J.
Publicado no Oncotarget (2016)

Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer

Por Nguyen, Dan JM., Theodoropoulos, George, Li, Ying-Ying, Wu, Chunjing, sha, Wei, Feun, Lynn G., Lampidis, Theodore J., Savaraj, Niramol, Wangpaichitr, Medhi
Publicado no Mol Cancer Res (2019)

Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LH(BETA)T(AG) retinal tumors

Por Piña, Yolanda, Houston, Samuel K, Murray, Timothy G, Koru-Sengul, Tulay, Decatur, Christina, Scott, William K, Nathanson, Lubov, Clarke, Jennifer, Lampidis, Theodore J
Publicado em 2012

Antiangiogenic Activity of 2-Deoxy-D-Glucose

Por Merchan, Jaime R., Kovács, Krisztina, Railsback, Jaclyn W., Kurtoglu, Metin, Jing, Yuqi, Piña, Yolanda, Gao, Ningguo, Murray, Timothy G., Lehrman, Mark A., Lampidis, Theodore J.
Publicado em 2010

Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1

Por Jiang, Chunhua, Moorthy, Balaji T., Patel, Devang M., Kumar, Akhilesh, Morgan, William M., Alfonso, Belkis, Huang, Jingyu, Lampidis, Theodore J., Isom, Daniel G., Barrientos, Antoni, Fontanesi, Flavia, Zhang, Fangliang
Publicado no Front Cell Dev Biol (2020)