Retinoblastoma treatment: impact of the glycolytic inhibitor 2-deoxy-d-glucose on molecular genomics expression in LH(BETA)T(AG) retinal tumors

PURPOSE: The purpose of this study was to evaluate the effect of 2-deoxy-D-glucose (2-DG) on the spatial distribution of the genetic expression of key elements involved in angiogenesis, hypoxia, cellular metabolism, and apoptosis in LH(BETA)T(AG) retinal tumors. METHODS: The right eye of each LH(BET...

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Bibliographic Details
Main Authors: Piña, Yolanda, Houston, Samuel K, Murray, Timothy G, Koru-Sengul, Tulay, Decatur, Christina, Scott, William K, Nathanson, Lubov, Clarke, Jennifer, Lampidis, Theodore J
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373226/
https://ncbi.nlm.nih.gov/pubmed/22701083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S29688
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