Advanced retinoblastoma treatment: targeting hypoxia by inhibition of the mammalian target of rapamycin (mTOR) in LH(BETA)T(AG) retinal tumors

PURPOSE: The purpose of this study is to analyze the dose response of the mammalian target of rapamycin (mTOR) inhibitor, rapamycin, on tumor burden and hypoxia, and study the treatment effect on vasculature in LH(BETA)T(AG) retinal tumors. METHODS: This study was approved by the Institutional Anima...

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Detaylı Bibliyografya
Asıl Yazarlar: Piña, Y, Decatur, C, Murray, TG, Houston, SK, Gologorsky, D, Cavalcante, M, Cavalcante, L, Hernandez, E, Celdran, M, Feuer, W, Lampidis, T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2011
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065577/
https://ncbi.nlm.nih.gov/pubmed/21468343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S16172
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