Advanced retinoblastoma treatment: targeting hypoxia by inhibition of the mammalian target of rapamycin (mTOR) in LH(BETA)T(AG) retinal tumors

PURPOSE: The purpose of this study is to analyze the dose response of the mammalian target of rapamycin (mTOR) inhibitor, rapamycin, on tumor burden and hypoxia, and study the treatment effect on vasculature in LH(BETA)T(AG) retinal tumors. METHODS: This study was approved by the Institutional Anima...

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Detalhes bibliográficos
Main Authors: Piña, Y, Decatur, C, Murray, TG, Houston, SK, Gologorsky, D, Cavalcante, M, Cavalcante, L, Hernandez, E, Celdran, M, Feuer, W, Lampidis, T
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065577/
https://ncbi.nlm.nih.gov/pubmed/21468343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S16172
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