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Inhibition of the Mechanistic Target of Rapamycin (mTOR)–Rapamycin and Beyond
Rapamycin is a Food and Drug Administration (FDA)-approved immunosuppressant and anticancer agent discovered in the soil of Easter Island in the early 1970s. Rapamycin is a potent and selective inhibitor of the mechanistic target of rapamycin (mTOR) protein kinase, which acts as a central integrator...
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| Udgivet i: | Cold Spring Harb Perspect Med |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852795/ https://ncbi.nlm.nih.gov/pubmed/27048303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025924 |
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