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Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases

Mechanistic target of rapamycin (mTOR, also known as mammalian target of rapamycin) is a ubiquitous serine/threonine kinase that regulates cell growth, proliferation and survival. These effects are cell-type-specific, and are elicited in response to stimulation by growth factors, hormones and cytoki...

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Detalhes bibliográficos
Publicado no:Nat Rev Rheumatol
Autor principal: Perl, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314913/
https://ncbi.nlm.nih.gov/pubmed/26698023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2015.172
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