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Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases
Mechanistic target of rapamycin (mTOR, also known as mammalian target of rapamycin) is a ubiquitous serine/threonine kinase that regulates cell growth, proliferation and survival. These effects are cell-type-specific, and are elicited in response to stimulation by growth factors, hormones and cytoki...
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| Pubblicato in: | Nat Rev Rheumatol |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5314913/ https://ncbi.nlm.nih.gov/pubmed/26698023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2015.172 |
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