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Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases

Mechanistic target of rapamycin (mTOR, also known as mammalian target of rapamycin) is a ubiquitous serine/threonine kinase that regulates cell growth, proliferation and survival. These effects are cell-type-specific, and are elicited in response to stimulation by growth factors, hormones and cytoki...

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Vydáno v:Nat Rev Rheumatol
Hlavní autor: Perl, Andras
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314913/
https://ncbi.nlm.nih.gov/pubmed/26698023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2015.172
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