Advanced retinoblastoma treatment: targeting hypoxia by inhibition of the mammalian target of rapamycin (mTOR) in LH(BETA)T(AG) retinal tumors

PURPOSE: The purpose of this study is to analyze the dose response of the mammalian target of rapamycin (mTOR) inhibitor, rapamycin, on tumor burden and hypoxia, and study the treatment effect on vasculature in LH(BETA)T(AG) retinal tumors. METHODS: This study was approved by the Institutional Anima...

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Bibliografiske detaljer
Main Authors: Piña, Y, Decatur, C, Murray, TG, Houston, SK, Gologorsky, D, Cavalcante, M, Cavalcante, L, Hernandez, E, Celdran, M, Feuer, W, Lampidis, T
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2011
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065577/
https://ncbi.nlm.nih.gov/pubmed/21468343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S16172
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