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N′(1),N′(3)-Dimethyl-N′(1),N′(3)-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (ROS)

Cisplatin is an important chemotherapeutic agent in lung cancer treatment. The mechanism of drug resistance to cisplatin is complex and historically has been difficult to overcome. We report here that cisplatin resistant lung cancer cell lines possess high basal levels of reactive oxygen species (RO...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wangpaichitr, Medhi, Wu, Chunjing, You, Min, Maher, Johnathan C., Dinh, Vy, Feun, Lynn G., Savaraj, Niramol
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Molecular Diversity Preservation International 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882109/
https://ncbi.nlm.nih.gov/pubmed/20535236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers1010023
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