Dual treatment with FLT3 inhibitor SU11657 and doxorubicin increases survival of leukemic mice

Por Lee, Brian D., Sevcikova, Sabina, Kogan, Scott C.
Publicado em 2006

TCEA1 regulates the proliferative potential of mouse myeloid cells

Por Yang, Taomei, Cui, Haoran, Wen, Mingxin, Zuber, Johannes, Kogan, Scott C, Wei, Guangwei
Publicado no Exp Cell Res (2018)

The PEBP2βMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia

Por Kogan, Scott C., Lagasse, Eric, Atwater, Susan, Bae, Suk-chul, Weissman, Irving, Ito, Yoshiaki, Bishop, J. Michael
Publicado em 1998

CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities

Por Lee, Young-Jin, Jones, Letetia C., Timchenko, Nikolai A., Perrotti, Danilo, Tenen, Daniel G., Kogan, Scott C.
Publicado em 2006

p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal

Por Zhao, Zhen, Zuber, Johannes, Diaz-Flores, Ernesto, Lintault, Laura, Kogan, Scott C., Shannon, Kevin, Lowe, Scott W.
Publicado em 2010

PML-RARα and Dnmt3a1 Cooperate in vivo to Promote Acute Promyelocytic Leukemia

Por Subramanyam, Deepa, Belair, Cassandra D., Barry-Holson, Keegan Q., Lin, Haijiang, Kogan, Scott C., Passegué, Emmanuelle, Blelloch, Robert
Publicado em 2010

Survival and tumorigenesis in O(6)-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure

Por Nagasubramanian, Ramamoorthy, Hansen, Ryan J., Delaney, Shannon M., Cherian, Mathew M., Samson, Leona D., Kogan, Scott C., Dolan, M. Eileen
Publicado em 2008

Pten loss in the bone marrow leads to G-CSF–mediated HSC mobilization

Por Tesio, Melania, Oser, Gabriela M., Baccelli, Irène, Blanco-Bose, William, Wu, Hong, Göthert, Joachim R., Kogan, Scott C., Trumpp, Andreas
Publicado em 2013

Determinants of Sensitivity and Resistance to Rapamycin-Chemotherapy Drug Combinations In vivo

Por Wendel, Hans-Guido, Malina, Abba, Zhao, Zhen, Zender, Lars, Kogan, Scott C., Cordon-Cardo, Carlos, Pelletier, Jerry, Lowe, Scott W.
Publicado no Cancer Res (2006)

Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia

Por Gaillard, Coline, Surianarayanan, Sangeetha, Bentley, Trevor, Warr, Matthew R., Fitch, Briana, Geng, Huimin, Passegué, Emmanuelle, de Thé, Hugues, Kogan, Scott C.
Publicado no Blood Adv (2018)

Retinoic Acid and Arsenic Synergize to Eradicate Leukemic Cells in a Mouse Model of Acute Promyelocytic Leukemia

Por Lallemand-Breitenbach, Valérie, Guillemin, Marie-Claude, Janin, Anne, Daniel, Marie-Thérèse, Degos, Laurent, Kogan, Scott C., Michael Bishop, J., de Thé, Hugues
Publicado em 1999

Direct and indirect targeting of MYC to treat acute myeloid leukemia

Por Brondfield, Sam, Umesh, Sushma, Corella, Alexandra, Zuber, Johannes, Rappaport, Amy R., Gaillard, Coline, Lowe, Scott W., Goga, Andrei, Kogan, Scott C.
Publicado no Cancer Chemother Pharmacol (2015)

Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA

Por Keeshan, Karen, Vieugué, Pauline, Chaudhury, Shahzya, Rishi, Loveena, Gaillard, Coline, Liang, Lu, Garcia, Elaine, Nakamura, Takuro, Omidvar, Nader, Kogan, Scott C.
Publicado no Haematologica (2016)

The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia

Por Arteaga, Maria Francisca, Mikesch, Jan-Henrik, Qiu, Jihui, Christensen, Jesper, Helin, Kristian, Kogan, Scott C., Dong, Shuo, So, Chi Wai Eric
Publicado no Cancer Cell (2013)

Treatment with 5-Azacytidine Accelerates Acute Promyelocytic Leukemia Leukemogenesis in a Transgenic Mouse Model

Por Scaglioni, Pier Paolo, Cai, Lu Fan, Majid, Samia M., Yung, Thomas M., Socci, Nicholas D., Kogan, Scott C., Kopelovich, Levy, Pandolfi, Pier Paolo
Publicado em 2011

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

Por Braun, Benjamin S., Tuveson, David A., Kong, Namie, Le, Doan T., Kogan, Scott C., Rozmus, Jacob, Le Beau, Michelle M., Jacks, Tyler E., Shannon, Kevin M.
Publicado em 2004

Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders

Por Joslin, John M., Fernald, Anthony A., Tennant, Thelma R., Davis, Elizabeth M., Kogan, Scott C., Anastasi, John, Crispino, John D., Le Beau, Michelle M.
Publicado em 2007

PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway

Por Huang, Ying, Hou, Jia-Kai, Chen, Ting-Ting, Zhao, Xu-Yun, Yan, Zhao-Wen, Zhang, Jing, Yang, Jie, Kogan, Scott C, Chen, Guo-Qiang
Publicado em 2011

Transcription and methylation analyses of preleukemic promyelocytes indicate a dual role for PML/RARA in leukemia initiation

Por Gaillard, Coline, Tokuyasu, Taku A., Rosen, Galit, Sotzen, Jason, Vitaliano-Prunier, Adeline, Roy, Ritu, Passegué, Emmanuelle, de Thé, Hugues, Figueroa, Maria E., Kogan, Scott C.
Publicado no Haematologica (2015)

Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice

Por Voisset, Edwige, Moravcsik, Eva, Stratford, Eva W., Jaye, Amie, Palgrave, Christopher J., Hills, Robert K., Salomoni, Paolo, Kogan, Scott C., Solomon, Ellen, Grimwade, David
Publicado no Blood (2018)