Direct and indirect targeting of MYC to treat acute myeloid leukemia

PURPOSE: Acute myeloid leukemia (AML) is the most common acute leukemia in adults and is often resistant to conventional therapies. The MYC oncogene is commonly overexpressed in AML but has remained an elusive target. We aimed to examine the consequences of targeting MYC both directly and indirectly...

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Bibliografiske detaljer
Udgivet i:Cancer Chemother Pharmacol
Main Authors: Brondfield, Sam, Umesh, Sushma, Corella, Alexandra, Zuber, Johannes, Rappaport, Amy R., Gaillard, Coline, Lowe, Scott W., Goga, Andrei, Kogan, Scott C.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485702/
https://ncbi.nlm.nih.gov/pubmed/25956709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2766-z
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