MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia

Recurring deletions of chromosome 7 and 7q [−7/del(7q)] occur in myelodysplastic syndromes and acute myeloid leukemia (AML) and are associated with poor prognosis. However, the identity of functionally relevant tumor suppressors on 7q remains unclear. Using RNAi and CRISPR/Cas9 approaches, we show t...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Chen, Chong, Liu, Yu, Rappaport, Amy R., Kitzing, Thomas, Schultz, Nikolaus, Zhao, Zhen, Shroff, Aditya S., Dickins, Ross A., Vakoc, Christopher R., Bradner, James E., Stock, Wendy, LeBeau, Michelle M., Shannon, Kevin M., Kogan, Scott, Zuber, Johannes, Lowe, Scott W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206212/
https://ncbi.nlm.nih.gov/pubmed/24794707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.03.016
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller