The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia

While all-trans retinoic acid (ATRA) treatment in acute promyelocytic leukemia (APL) has been the paradigm of targeted therapy for oncogenic transcription factors, the underlying mechanisms remain largely unknown, and a significant number of patients still relapse and become ATRA resistant. We ident...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Arteaga, Maria Francisca, Mikesch, Jan-Henrik, Qiu, Jihui, Christensen, Jesper, Helin, Kristian, Kogan, Scott C., Dong, Shuo, So, Chi Wai Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812572/
https://ncbi.nlm.nih.gov/pubmed/23518351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.02.014
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