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Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

The enzymes catalyzing lysine and arginine methylation of histones are essential for maintaining transcriptional programs and determining cell fate and identity. Until recently, histone methylation was regarded irreversible. However, within the last few years, several families of histone demethylase...

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Autors principals: Cloos, Paul A.C., Christensen, Jesper, Agger, Karl, Helin, Kristian
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732404/
https://ncbi.nlm.nih.gov/pubmed/18451103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1652908
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