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Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

The enzymes catalyzing lysine and arginine methylation of histones are essential for maintaining transcriptional programs and determining cell fate and identity. Until recently, histone methylation was regarded irreversible. However, within the last few years, several families of histone demethylase...

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Autori principali: Cloos, Paul A.C., Christensen, Jesper, Agger, Karl, Helin, Kristian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732404/
https://ncbi.nlm.nih.gov/pubmed/18451103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1652908
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