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Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

The enzymes catalyzing lysine and arginine methylation of histones are essential for maintaining transcriptional programs and determining cell fate and identity. Until recently, histone methylation was regarded irreversible. However, within the last few years, several families of histone demethylase...

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Bibliografiske detaljer
Main Authors: Cloos, Paul A.C., Christensen, Jesper, Agger, Karl, Helin, Kristian
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732404/
https://ncbi.nlm.nih.gov/pubmed/18451103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1652908
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