Prognosis and Therapy When Acute Promyelocytic Leukemia and Other “Good Risk” Acute Myeloid Leukemias Occur as a Therapy-Related Myeloid Neoplasm

Por Larson, Richard A., Le Beau, Michelle M.
Publicado em 2011

BMP meets AML: induction of BMP signaling by a novel fusion gene promotes pediatric acute leukemia

Por Crispino, John D., Le Beau, Michelle M.
Publicado em 2012

Myelodysplastic Syndromes

Por Odenike, Olatoyosi, Anastasi, John, Le Beau, Michelle M.
Publicado no Clin Lab Med (2011)

Haploinsufficiency of Apc leads to ineffective hematopoiesis

Por Wang, Jianghong, Fernald, Anthony A., Anastasi, John, Le Beau, Michelle M., Qian, Zhijian
Publicado em 2010

A critical role for Apc in hematopoietic stem and progenitor cell survival

Por Qian, Zhijian, Chen, Lina, Fernald, Anthony A., Williams, Bart O., Le Beau, Michelle M.
Publicado em 2008

Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms

Por Stoddart, Angela, Nakitandwe, Joy, Chen, Shann-Ching, Downing, James R., Le Beau, Michelle M.
Publicado no Blood (2015)

Expression profiling of CD34(+) hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia

Por Qian, Zhijian, Fernald, Anthony A., Godley, Lucy A., Larson, Richard A., Le Beau, Michelle M.
Publicado em 2002

Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc

Por Stoddart, Angela, Wang, Jianghong, Fernald, Anthony A., Karrison, Theodore, Anastasi, John, Le Beau, Michelle M.
Publicado em 2014

Myelodysplastic syndromes

Por Deeg, H. Joachim., Bowen, David T., Gore, Steven D., Haferlach, Torsten., Le Beau, Michelle M., Niemeyer, Charlotte.

The Clathrin-Binding Domain of CALM-AF10 Alters the Phenotype of Myeloid Neoplasms in Mice

Por Stoddart, Angela, Tennant, Thelma R., Fernald, Anthony A., Anastasi, John, Brodsky, Frances, Le Beau, Michelle M.
Publicado em 2011

Activation of Wnt/β-Catenin Protein Signaling Induces Mitochondria-mediated Apoptosis in Hematopoietic Progenitor Cells

Por Ming, Ming, Wang, Sheng, Wu, Wenshu, Senyuk, Vitalyi, Le Beau, Michelle M., Nucifora, Giuseppina, Qian, Zhijian
Publicado em 2012

A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy

Por Boyapati, Anita, Yan, Ming, Peterson, Luke F., Biggs, Joseph R., Le Beau, Michelle M., Zhang, Dong-Er
Publicado em 2007

Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

Por Kirsammer, Gina, Jilani, Sarah, Liu, Hui, Davis, Elizabeth, Gurbuxani, Sandeep, Le Beau, Michelle M., Crispino, John D.
Publicado em 2008

High-throughput mapping of origins of replication in human cells

Por Lucas, Isabelle, Palakodeti, Aparna, Jiang, Yanwen, Young, David J, Jiang, Nan, Fernald, Anthony A, Le Beau, Michelle M
Publicado em 2007

Common fragile sites are characterized by histone hypoacetylation

Por Jiang, Yanwen, Lucas, Isabelle, Young, David J., Davis, Elizabeth M., Karrison, Theodore, Rest, Joshua S., Le Beau, Michelle M.
Publicado em 2009

Impaired replication dynamics at the FRA3B common fragile site

Por Palakodeti, Aparna, Lucas, Isabelle, Jiang, Yanwen, Young, David J., Fernald, Anthony A., Karrison, Theodore, Le Beau, Michelle M.
Publicado em 2010

Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice

Por Stoddart, Angela, Fernald, Anthony A., Wang, Jianghong, Davis, Elizabeth M., Karrison, Theodore, Anastasi, John, Le Beau, Michelle M.
Publicado em 2014

Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1–1.5 Mb and preparation of a PAC-based physical map

Por Zhao, Nanding, Stoffel, Archontoula, Wang, Pauline W., Eisenbart, James D., Espinosa, Rafael, Larson, Richard A., Le Beau, Michelle M.
Publicado em 1997

Interstitial uniparental isodisomy at clustered breakpoint intervals is a frequent mechanism of NF1 inactivation in myeloid malignancies

Por Stephens, Karen, Weaver, Molly, Leppig, Kathleen A., Maruyama, Kyoko, Emanuel, Peter D., Le Beau, Michelle M., Shannon, Kevin M.
Publicado em 2006

Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts

Por Young, David J., Stoddart, Angela, Nakitandwe, Joy, Chen, Shann-Ching, Qian, Zhijian, Downing, James R., Le Beau, Michelle M.
Publicado em 2014