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High-throughput mapping of origins of replication in human cells

Mapping origins of replication has been challenging in higher eukaryotes. We have developed a rapid, genome-wide method to map origins of replication in asynchronous human cells by combining the nascent strand abundance assay with a highly tiled microarray platform, and we validated the technique by...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lucas, Isabelle, Palakodeti, Aparna, Jiang, Yanwen, Young, David J, Jiang, Nan, Fernald, Anthony A, Le Beau, Michelle M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978075/
https://ncbi.nlm.nih.gov/pubmed/17668008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401026
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