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Impaired replication dynamics at the FRA3B common fragile site
Chromosomal common fragile sites (CFSs) are genetically unstable regions of the genome that are induced by conditions that impair DNA replication. In this report, we show that treatment with the DNA polymerase inhibitor, aphidicolin (APH), slows the replication rate throughout S phase. To investigat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800779/ https://ncbi.nlm.nih.gov/pubmed/19815620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp470 |
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