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Common fragile sites are characterized by histone hypoacetylation
Common fragile sites (CFSs) represent large, highly unstable regions of the human genome. CFS sequences are sensitive to perturbation of replication; however, the molecular basis for the instability at CFSs is poorly understood. We hypothesized that a unique epigenetic pattern may underlie the unusu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773265/ https://ncbi.nlm.nih.gov/pubmed/19717471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp410 |
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