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Common fragile sites are characterized by histone hypoacetylation

Common fragile sites (CFSs) represent large, highly unstable regions of the human genome. CFS sequences are sensitive to perturbation of replication; however, the molecular basis for the instability at CFSs is poorly understood. We hypothesized that a unique epigenetic pattern may underlie the unusu...

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Bibliografski detalji
Glavni autori: Jiang, Yanwen, Lucas, Isabelle, Young, David J., Davis, Elizabeth M., Karrison, Theodore, Rest, Joshua S., Le Beau, Michelle M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773265/
https://ncbi.nlm.nih.gov/pubmed/19717471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp410
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