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Updating the mechanisms of common fragile site instability: how to reconcile the different views?

Common fragile sites (CFSs) are large chromosomal regions long identified by conventional cytogenetics as sequences prone to breakage in cells subjected to replication stress. The interest in CFSs came from their key role in the formation of DNA damage, resulting in chromosomal rearrangements. The i...

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Vydáno v:Cell Mol Life Sci
Hlavní autoři: Le Tallec, Benoît, Koundrioukoff, Stéphane, Wilhelm, Therese, Letessier, Anne, Brison, Olivier, Debatisse, Michelle
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Basel 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232738/
https://ncbi.nlm.nih.gov/pubmed/25248392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-014-1720-2
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