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Genome Instability at Common Fragile Sites: Searching for the Cause of Their Instability

Common fragile sites (CFS) are heritable nonrandomly distributed loci on human chromosomes that exhibit an increased frequency of chromosomal breakage under conditions of replication stress. They are considered the preferential targets for high genomic instability from the earliest stages of human c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Franchitto, Annapaola
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780545/
https://ncbi.nlm.nih.gov/pubmed/24083238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/730714
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