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Impaired Replication Timing Promotes Tissue-Specific Expression of Common Fragile Sites

Common fragile sites (CFSs) are particularly vulnerable regions of the genome that become visible as breaks, gaps, or constrictions on metaphase chromosomes when cells are under replicative stress. Impairment in DNA replication, late replication timing, enrichment of A/T nucleotides that tend to for...

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Podrobná bibliografie
Vydáno v:Genes (Basel)
Hlavní autoři: Maccaroni, Klizia, Balzano, Elisa, Mirimao, Federica, Giunta, Simona, Pelliccia, Franca
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140878/
https://ncbi.nlm.nih.gov/pubmed/32204553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11030326
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