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Replication Stress Response Links RAD52 to Protecting Common Fragile Sites

Rad52 in yeast is a key player in homologous recombination (HR), but mammalian RAD52 is dispensable for HR as shown by the lack of a strong HR phenotype in RAD52-deficient cells and in RAD52 knockout mice. RAD52 function in mammalian cells first emerged with the discovery of its important backup rol...

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Detaylı Bibliyografya
Yayımlandı:Cancers (Basel)
Yazar: Wu, Xiaohua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826974/
https://ncbi.nlm.nih.gov/pubmed/31569559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101467
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