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High-throughput mapping of origins of replication in human cells
Mapping origins of replication has been challenging in higher eukaryotes. We have developed a rapid, genome-wide method to map origins of replication in asynchronous human cells by combining the nascent strand abundance assay with a highly tiled microarray platform, and we validated the technique by...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978075/ https://ncbi.nlm.nih.gov/pubmed/17668008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401026 |
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