Integrated Analysis of Intracellular Dynamics of MenaINV Cancer Cells in a 3D Matrix

Por Mak, Michael, Anderson, Sarah, McDonough, Meghan C., Spill, Fabian, Kim, Jessica E., Boussommier-Calleja, Alexandra, Zaman, Muhammad H., Kamm, Roger D.
Publicado no Biophys J (2017)

Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design

Por Koh, Cho Yeow, Kim, Jessica E., Napoli, Alberto J., Verlinde, Christophe L.M.J., Fan, Erkang, Buckner, Frederick S., Van Voorhis, Wesley C., Hol, Wim G.J.
Publicado em 2013

Distinct states of methionyl-tRNA synthetase indicates inhibitor binding by conformational selection

Por Koh, Cho Yeow, Kim, Jessica E., Shibata, Sayaka, Ranade, Ranae M., Yu, Mingyan, Liu, Jiyun, Gillespie, J. Robert, Buckner, Frederick S., Verlinde, Christophe L.M.J., Fan, Erkang, Hol, Wim G.J.
Publicado em 2012

Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia

Por Larson, Eric T., Kim, Jessica E., Napuli, Alberto J., Verlinde, Christophe L. M. J., Fan, Erkang, Zucker, Frank H., Van Voorhis, Wesley C., Buckner, Frederick S., Hol, Wim G. J., Merritt, Ethan A.
Publicado em 2012

Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase

Por Merritt, Ethan A, Arakaki, Tracy L, Gillespie, Robert, Napuli, Alberto J, Kim, Jessica E, Buckner, Frederick S, Van Voorhis, Wesley C, Verlinde, Christophe L M J, Fan, Erkang, Zucker, Frank, Hol, Wim G J
Publicado em 2011

Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization

Por Shibata, Sayaka, Gillespie, J. Robert, Ranade, Ranae M., Koh, Cho Yeow, Kim, Jessica E., Laydbak, Joy U., Zucker, Frank H., Hol, Wim G. J., Verlinde, Christophe L. M. J., Buckner, Frederick S., Fan, Erkang
Publicado em 2012

The double-length tyrosyl-tRNA synthetase from the eukaryote Leishmania major forms an intrinsically asymmetric pseudo-dimer

Por Larson, Eric T, Kim, Jessica E, Castaneda, Lisa J, Napuli, Alberto J, Zhang, Zhongsheng, Fan, Erkang, Zucker, Frank H, Verlinde, Christophe LMJ, Buckner, Frederick S, Van Voorhis, Wesley C, Hol, Wim G J, Merritt, Ethan A
Publicado em 2011

Structure of Leishmania major Methionyl-tRNA Synthetase in Complex with Intermediate Products Methionyladenylate and Pyrophosphate

Por Larson, Eric T., Kim, Jessica E., Zucker, Frank H., Kelley, Angela, Mueller, Natascha, Napuli, Alberto J., Verlinde, Christophe L.M.J., Fan, Erkang, Buckner, Frederick S., Van Voorhis, Wesley C., Merritt, Ethan A., Hol, Wim G.J.
Publicado em 2010

Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness

Por Koh, Cho Yeow, Kim, Jessica E., Wetzel, Allan B., de van der Schueren, Will J., Shibata, Sayaka, Ranade, Ranae M., Liu, Jiyun, Zhang, Zhongsheng, Gillespie, J. Robert, Buckner, Frederick S., Verlinde, Christophe L. M. J., Fan, Erkang, Hol, Wim G. J.
Publicado em 2014

Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii

Por Murphy, Ryan C., Ojo, Kayode K., Larson, Eric T., Castellanos-Gonzalez, Alejandro, Perera, B. Gayani K., Keyloun, Katelyn R., Kim, Jessica E., Bhandari, Janhavi G., Muller, Natascha R., Verlinde, Christophe L. M. J., White, A. Clinton, Merritt, Ethan A., Van Voorhis, Wesley C., Maly, Dustin J.
Publicado em 2010

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

Por Ojo, Kayode K, Larson, Eric T, Keyloun, Katelyn R, Castaneda, Lisa J, DeRocher, Amy E, Inampudi, Krishna K, Kim, Jessica E, Arakaki, Tracy L, Murphy, Ryan C, Zhang, Li, Napuli, Alberto J, Maly, Dustin J, Verlinde, Christophe LMJ, Buckner, Frederick S, Parsons, Marilyn, Hol, Wim GJ, Merritt, Ethan A, Van Voorhis, Wesley C
Publicado em 2010

Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1

Por Larson, Eric T., Ojo, Kayode K., Murphy, Ryan C., Johnson, Steven M., Zhang, Zhongsheng, Kim, Jessica E., Leibly, David J., Fox, Anna M. W., Reid, Molly C., Dale, Edward J., Perera, B. Gayani K., Kim, Jae, Hewitt, Stephen N., Hol, Wim G. J., Verlinde, Christophe L. M. J., Fan, Erkang, Van Voorhis, Wesley C., Maly, Dustin J., Merritt, Ethan A.
Publicado em 2012