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Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design

Malaria, most commonly caused by the parasite Plasmodium falciparum, is a devastating disease that remains a large global health burden. Lack of vaccines and drug resistance necessitate the continual development of new drugs and exploration of new drug targets. Due to their essential role in protein...

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Detalhes bibliográficos
Main Authors: Koh, Cho Yeow, Kim, Jessica E., Napoli, Alberto J., Verlinde, Christophe L.M.J., Fan, Erkang, Buckner, Frederick S., Van Voorhis, Wesley C., Hol, Wim G.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680109/
https://ncbi.nlm.nih.gov/pubmed/23665145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2013.04.007
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