Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1

Diseases caused by the apicomplexan protozoans Toxoplasma gondii and Cryptosporidium parvum are a major health concern. The life cycle of these parasites is regulated by a family of calcium-dependent protein kinases (CDPKs) that have no direct homologs in the human host. Fortuitously, CDPK1 from bot...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Larson, Eric T., Ojo, Kayode K., Murphy, Ryan C., Johnson, Steven M., Zhang, Zhongsheng, Kim, Jessica E., Leibly, David J., Fox, Anna M. W., Reid, Molly C., Dale, Edward J., Perera, B. Gayani K., Kim, Jae, Hewitt, Stephen N., Hol, Wim G. J., Verlinde, Christophe L. M. J., Fan, Erkang, Van Voorhis, Wesley C., Maly, Dustin J., Merritt, Ethan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336864/
https://ncbi.nlm.nih.gov/pubmed/22369268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201725v
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados