Development of Potent and Selective Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (PfCDPK4) Inhibitors that Block the Transmission of Malaria to Mosquitoes

Malaria remains a major health concern for a large percentage of the world’s population. While great strides have been made in reducing mortality due to malaria, new strategies and therapies are still needed. Therapies that are capable of blocking the transmission of Plasmodium parasites are particu...

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Main Authors: Vidadala, Rama Subba Rao, Ojo, Kayode K., Johnson, Steven M., Zhang, Zhongsheng, Leonard, Stephen E., Mitra, Arinjay, Choi, Ryan, Reid, Molly C., Keyloun, Katelyn R., Fox, Anna M.W., Kennedy, Mark, Silver-Brace, Tiffany, Hume, Jen C. C., Kappe, Stefan, Verlinde, Christophe L.M.J., Fan, Erkang, Merritt, Ethan A., Van Voorhis, Wesley C., Maly, Dustin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024383/
https://ncbi.nlm.nih.gov/pubmed/24531197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.12.048
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