The double-length tyrosyl-tRNA synthetase from the eukaryote Leishmania major forms an intrinsically asymmetric pseudo-dimer

The single tyrosyl tRNA-synthetase (TyrRS) gene in trypanosomatid genomes codes for a protein that is twice the length of TyrRS from virtually all other organisms. Each half of the double-length TyrRS contains a catalytic domain and an anticodon-binding domain, however the two halves retain only 17%...

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Detalhes bibliográficos
Main Authors: Larson, Eric T, Kim, Jessica E, Castaneda, Lisa J, Napuli, Alberto J, Zhang, Zhongsheng, Fan, Erkang, Zucker, Frank H, Verlinde, Christophe LMJ, Buckner, Frederick S, Van Voorhis, Wesley C, Hol, Wim G J, Merritt, Ethan A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095712/
https://ncbi.nlm.nih.gov/pubmed/21420975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.026
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