Biochemical Mechanisms of Resistance to Small-Molecule Protein Kinase Inhibitors

Por Krishnamurty, Ratika, Maly, Dustin J.
Publicado em 2010

Druggable Sensors of the Unfolded Protein Response

Por Maly, Dustin J., Papa, Feroz R.
Publicado no Nat Chem Biol (2014)

Affinity Reagents that Target a Specific Inactive Form of Protein Kinases

Por Ranjitkar, Pratistha, Brock, Amanda M., Maly, Dustin J.
Publicado em 2010

Protein kinase affinity reagents based on a 5-aminoindazole scaffold

Por Krishnamurty, Ratika, Brock, Amanda M., Maly, Dustin J.
Publicado em 2010

Determination of the Kinetics and Thermodynamics of Ligand Binding to a Specific Inactive Conformation in Protein Kinases

Por Hari, Sanjay B., Ranjitkar, Pratistha, Maly, Dustin J.
Publicado no Methods Mol Biol (2012)

Combinatorial target-guided ligand assembly: Identification of potent subtype-selective c-Src inhibitors

Por Maly, Dustin J., Choong, Ingrid C., Ellman, Jonathan A.
Publicado em 2000

Sequence Determinants of a Specific Inactive Protein Kinase Conformation

Por Hari, Sanjay B., Merritt, Ethan A., Maly, Dustin J.
Publicado em 2013

Conformation-Selective ATP-Competitive Inhibitors Control Regulatory Interactions and Noncatalytic Functions of Mitogen-Activated Protein Kinases

Por Hari, Sanjay B., Merritt, Ethan A., Maly, Dustin J.
Publicado em 2014

SH2-Catalytic Domain Linker Heterogeneity Influences Allosteric Coupling across the SFK Family

Por Register, A. C., Leonard, Stephen E., Maly, Dustin J.
Publicado no Biochemistry (2014)

Bivalent inhibitors of the tyrosine kinases ABL and SRC: Determinants of potency and selectivity

Por Hill, Zachary B., Perera, B. Gayani K., Maly, Dustin J.
Publicado em 2010

A Hexylchloride-Based Catch-and-Release System for Chemical Proteomic Applications

Por Brigham, Jennifer L., Perera, B. Gayani K., Maly, Dustin J.
Publicado em 2013

Bivalent Inhibitors of Protein Kinases

Por Gower, Carrie M., Chang, Matthew E. K., Maly, Dustin J.
Publicado no Crit Rev Biochem Mol Biol (2014)

Targeting Diverse Signaling Interaction Sites Allows the Rapid Generation of Bivalent Kinase Inhibitors

Por Hill, Zachary B., Perera, B. Gayani K., Andrews, Simeon S., Maly, Dustin J.
Publicado em 2011

Label Transfer Reagents to Probe p38 MAPK Binding Partners

Por Andrews, Simeon S., Hill, Zachary B., Perera, B. Gayani K., Maly, Dustin J.
Publicado em 2013

Divergent Modulation of Src-Family Kinase Regulatory Interactions with ATP-Competitive Inhibitors

Por Leonard, Stephen E., Register, A. C., Krishnamurty, Ratika, Brighty, Gabriel J., Maly, Dustin J.
Publicado em 2014

A novel protein kinase is essential in bloodstream Trypanosoma brucei

Por Jensen, Bryan C., Booster, Nick, Vidadala, Rama Subba Rao, Maly, Dustin J., Parsons, Marilyn
Publicado no Int J Parasitol (2016)

Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing

Por Rose, John C., Stephany, Jason J., Wei, Cindy T., Fowler, Douglas M., Maly, Dustin J.
Publicado no ACS Chem Biol (2017)

Conformation-selective inhibitors reveal differences in the activation and phosphate-binding loops of the tyrosine kinases Abl and Src

Por Hari, Sanjay B., Perera, B. Gayani K., Ranjitkar, Pratistha, Seeliger, Markus A., Maly, Dustin J.
Publicado em 2013

Bumped Kinase Inhibitor 1294 Treats Established Toxoplasma gondii Infection

Por Doggett, J. Stone, Ojo, Kayode K., Fan, Erkang, Maly, Dustin J., Van Voorhis, Wesley C.
Publicado em 2014

Intracellular Delivery of Bioactive Molecules using Light-Addressable Nanocapsules

Por Gregersen, Kimberly A. D., Hill, Zachary B., Gadd, Jennifer C., Fujimoto, Bryant S., Maly, Dustin J., Chiu, Daniel T.
Publicado em 2010