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Biochemical Mechanisms of Resistance to Small-Molecule Protein Kinase Inhibitors
Protein kinases have emerged as one of the most frequently targeted families of proteins in drug discovery. While the development of small-molecule inhibitors that have the potency and selectivity necessary to be effective cancer drugs is still a formidable challenge, there have been several notable...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879594/ https://ncbi.nlm.nih.gov/pubmed/20044834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb9002656 |
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