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Divergent Modulation of Src-Family Kinase Regulatory Interactions with ATP-Competitive Inhibitors

[Image: see text] Multidomain protein kinases, central controllers of signal transduction, use regulatory domains to modulate catalytic activity in a complex cellular environment. Additionally, these domains regulate noncatalytic functions, including cellular localization and protein–protein interac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leonard, Stephen E., Register, A. C., Krishnamurty, Ratika, Brighty, Gabriel J., Maly, Dustin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136698/
https://ncbi.nlm.nih.gov/pubmed/24946274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500371g
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