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Bivalent Inhibitors of Protein Kinases

Protein kinases are key players in a large number of cellular signaling pathways. Dysregulated kinase activity has been implicated in a number of diseases, and members of this enzyme family are of therapeutic interest. However, due to the fact that most inhibitors interact with the highly conserved...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Gower, Carrie M., Chang, Matthew E. K., Maly, Dustin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627631/
https://ncbi.nlm.nih.gov/pubmed/24564382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2013.875513
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