A carregar...

Determination of the Kinetics and Thermodynamics of Ligand Binding to a Specific Inactive Conformation in Protein Kinases

Recent interest in inactive kinase conformations has generated the need to develop new biophysical tools to study them. Here, we describe the use of a fluorescent probe that selectively and potently binds to kinases in inactive, “DFG-out” conformations to obtain valuable thermodynamic and kinetic in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Hari, Sanjay B., Ranjitkar, Pratistha, Maly, Dustin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228460/
https://ncbi.nlm.nih.gov/pubmed/22956140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-008-3_12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!