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Biomolecular conformational changes and ligand binding: from kinetics to thermodynamics

The behaviour of biomolecular systems is governed by their thermodynamic and kinetic properties. It is thus important to be able to calculate, for example, both the affinity and rate of binding and dissociation of a protein–ligand complex, or the populations and exchange rates between distinct confo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Wang, Yong, Martins, João Miguel, Lindorff-Larsen, Kresten
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859887/
https://ncbi.nlm.nih.gov/pubmed/29619200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01627a
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