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Biomolecular conformational changes and ligand binding: from kinetics to thermodynamics

The behaviour of biomolecular systems is governed by their thermodynamic and kinetic properties. It is thus important to be able to calculate, for example, both the affinity and rate of binding and dissociation of a protein–ligand complex, or the populations and exchange rates between distinct confo...

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Bibliografiska uppgifter
I publikationen:Chem Sci
Huvudupphovsmän: Wang, Yong, Martins, João Miguel, Lindorff-Larsen, Kresten
Materialtyp: Artigo
Språk:Inglês
Publicerad: Royal Society of Chemistry 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859887/
https://ncbi.nlm.nih.gov/pubmed/29619200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01627a
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