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Biomolecular conformational changes and ligand binding: from kinetics to thermodynamics
The behaviour of biomolecular systems is governed by their thermodynamic and kinetic properties. It is thus important to be able to calculate, for example, both the affinity and rate of binding and dissociation of a protein–ligand complex, or the populations and exchange rates between distinct confo...
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| Опубликовано в: : | Chem Sci |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Royal Society of Chemistry
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859887/ https://ncbi.nlm.nih.gov/pubmed/29619200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01627a |
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