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A novel protein kinase is essential in bloodstream Trypanosoma brucei
Human African trypanosomiasis a fatal disease for which no vaccines exist and treatment regimens are difficult. Here, we evaluate a Trypanosoma brucei protein kinase, AEK1, as a potential drug target. Conditional knockouts confirmed AEK1 essentiality in bloodstream forms. For chemical validation, we...
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| Published in: | Int J Parasitol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925258/ https://ncbi.nlm.nih.gov/pubmed/27018127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2016.03.001 |
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